I’m excited to share with you some of the Institute’s latest news! With the support of our donors and the State of Nevada, we continue to make critical progress in the diagnosis and treatment of ME/CFS, a complex and disabling disease process. The Institute participated in a recently published retrospective study identifying specific biomarkers from [...]
Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity.
Authors: Singh S, Stafford P, Schlauch KA, Tillett RR, Gollery M, Johnston SA, Khaiboullina SF, De Meirleir KL, Rawat S, Mijatovic T, Subramanian K, Palotás A, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/29886183 Publication: Mol Neurobiol. 2018 Jan;55(1):633-641. doi: 10.1007/s12035-016-0334-0. Epub 2016 Dec 15. Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers [...]
Nutritional modulation of the intestinal microbiota; future opportunities for the prevention and treatment of neuroimmune and neuroinflammatory disease.
Authors: Lombardi VC, De Meirleir KL, Subramanian K, Nourani SM, Dagda RK, Delaney SL, Palotás A. Link: https://www.ncbi.nlm.nih.gov/pubmed/29886183 Publication: J Nutr Biochem. 2018 Apr 19;61:1-16. doi: 10.1016/j.jnutbio.2018.04.004. [Epub ahead of print] The gut-brain axis refers to the bidirectional communication between the enteric nervous system and the central nervous system. Mounting evidence supports the premise that the intestinal microbiota [...]
Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases.
Authors: Schlauch KA, Kulick D, Subramanian K, De Meirleir KL, Palotás A, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/30120429 Publication: Int J Obes (Lond). 2018 Aug 17. doi: 10.1038/s41366-018-0181-3. [Epub ahead of print] BACKGROUND/OBJECTIVES: Obesity is an important risk factor for the development of diseases such as diabetes mellitus, hypertension, and dyslipidemia; however, a small number of individuals with long-standing [...]
Post-treatment Lyme disease (PTLD) or chronic Lyme disease is the name for a group of chronic symptoms that may occur after taking the antibiotic treatment for an acute episode of Lyme disease. Ticks carry multiple bacterial pathogens in their saliva including Borrelia, the pathogen which causes Lyme disease. They transmit these infections to humans by [...]